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A driven young medical resident transfers to a rural hospital for a fresh start. There, the demons of his past start to catch up to him when he becomes consumed by the case of a young asthma patient.

Helen, a writer, and Madeline, an actress, have hated each other for years. Madeline is married to Ernest, who was once Helen’s fiance. After she recovers from a mental breakdown, Helen vows revenge by stealing back Ernest and plotting to kill Madeline. Both rivals have secretly drunk a miracle cure for aging; they accidentally discover, when each tries to eliminate the other, that they have become immortal and that “life” will never be the same again.