A bout between Junior dos Santos and Shane Carwin will headline the event. The winner of the fight is expected to face off against current UFC Heavyweight Champion Cain Velasquez. Brock Lesnar was scheduled to fight Dos Santos after their coaching stint on The Ultimate Fighter 13, but due to a reoccurring illness he was replaced by Carwin. Originally, a matchup between Carwin and Jon Olav Einemo was scheduled for this event. Einemo will remain on the card and now be fighting Dave Herman, who was pulled from a matchup with Joey Beltran as a result. Beltran will now be matched up against Aaron Rosa.